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granulocyte images: illustrations and micrographs. All credits and licenses listed.

Micrographs

Neutrophil in a peripheral blood smear, Wright stain. The multilobed nucleus and pale cytoplasm are characteristic of the circulating PMN.

Neutrophil in a peripheral blood smear, Wright stain. The multilobed nucleus and pale cytoplasm are characteristic of the circulating PMN.

Bob Blaylock, Wikimedia Commons · CC BY-SA 3.0 · source

Amini, Schemmelmann, Heming et al 2025, JCI Insight · CC BY 4.0 · source

Neutrophil in a peripheral blood smear showing the characteristic segmented nucleus with 3 to 5 lobes.

Neutrophil in a peripheral blood smear showing the characteristic segmented nucleus with 3 to 5 lobes.

Dr. Roshan Nasimudeen, Wikimedia Commons · CC BY-SA 3.0 · source

Scanning electron micrograph of a human neutrophil (blue) engulfing MRSA bacteria (yellow). The cell extends pseudopods around the bacteria in a classic phagocytic embrace.

Scanning electron micrograph of a human neutrophil (blue) engulfing MRSA bacteria (yellow). The cell extends pseudopods around the bacteria in a classic phagocytic embrace.

National Institutes of Health (NIH) · Public domain · source

Scanning electron micrograph of a neutrophil (orange-brown) with MRSA bacteria (purple). A second image from the NIH SEM series on neutrophil-pathogen interaction.

Scanning electron micrograph of a neutrophil (orange-brown) with MRSA bacteria (purple). A second image from the NIH SEM series on neutrophil-pathogen interaction.

National Institutes of Health (NIH) · Public domain · source

Scanning electron micrograph of a neutrophil (orange) engaging a Bacillus anthracis chain (green). Taken by Volker Brinkmann, the scientist who discovered neutrophil extracellular traps.

Scanning electron micrograph of a neutrophil (orange) engaging a Bacillus anthracis chain (green). Taken by Volker Brinkmann, the scientist who discovered neutrophil extracellular traps.

Volker Brinkmann, Wikimedia Commons · CC BY 2.5 · source

Scanning electron micrograph of neutrophil extracellular traps (NETs): fine fibres of decondensed chromatin with embedded granule proteins enmeshing Staphylococcus aureus.

Scanning electron micrograph of neutrophil extracellular traps (NETs): fine fibres of decondensed chromatin with embedded granule proteins enmeshing Staphylococcus aureus.

Urban CF et al. 2009, PLoS Pathogens, Wikimedia Commons · CC BY 2.5 · source

Immunofluorescence of NETs: neutrophils (blue DAPI nuclei) releasing decondensed chromatin co-stained with MPO (red) and citrullinated histone H3 (green).

Immunofluorescence of NETs: neutrophils (blue DAPI nuclei) releasing decondensed chromatin co-stained with MPO (red) and citrullinated histone H3 (green).

Singh, Zlatar, Munoz-Becerra et al 2024, Cell Communication and Signaling · CC BY 4.0 · source

Transmission electron micrograph of a human neutrophil showing the multilobed nucleus and electron-dense azurophilic granules in the cytoplasm.

Transmission electron micrograph of a human neutrophil showing the multilobed nucleus and electron-dense azurophilic granules in the cytoplasm.

Serwas, Huemer, Dieckmann et al 2018, Frontiers in Immunology · CC BY · source

Immunoelectron micrograph of a neutrophil granule showing immunogold labeling of specific granule contents. Granule populations are distinguished by their electron density and marker proteins.

Immunoelectron micrograph of a neutrophil granule showing immunogold labeling of specific granule contents. Granule populations are distinguished by their electron density and marker proteins.

Serwas, Huemer, Dieckmann et al 2018, Frontiers in Immunology · CC BY · source

Eosinophil in a peripheral blood smear, Giemsa stain. The bilobed nucleus and large brick-red granules packed with major basic protein are the defining features.

Eosinophil in a peripheral blood smear, Giemsa stain. The bilobed nucleus and large brick-red granules packed with major basic protein are the defining features.

Bobjgalindo, Wikimedia Commons · CC BY-SA 4.0 · source

Eosinophil among red blood cells, Giemsa stain. The bright orange-red cytoplasmic granules are visible against the pale erythrocytes.

Eosinophil among red blood cells, Giemsa stain. The bright orange-red cytoplasmic granules are visible against the pale erythrocytes.

Dr Graham Beards, Wikimedia Commons · CC BY-SA 3.0 · source

Activated eosinophils in idiopathic hypereosinophilic syndrome. Degranulated cells with vacuolated cytoplasm; some show extracellular granule deposits, a hallmark of cytolytic degranulation.

Activated eosinophils in idiopathic hypereosinophilic syndrome. Degranulated cells with vacuolated cytoplasm; some show extracellular granule deposits, a hallmark of cytolytic degranulation.

NIAID, Wikimedia Commons · CC BY 2.0 · source

Transmission electron micrograph of a human eosinophil showing granules with their characteristic crystalloid core (major basic protein) surrounded by a less-dense matrix.

Transmission electron micrograph of a human eosinophil showing granules with their characteristic crystalloid core (major basic protein) surrounded by a less-dense matrix.

Neves, Palazzi, Malta et al 2024, Journal of Leukocyte Biology · CC BY 4.0 · source

Transmission electron micrograph showing eosinophil cytolytic degranulation: free extracellular granules with intact crystalloid cores, released by cell lysis rather than classical exocytosis.

Transmission electron micrograph showing eosinophil cytolytic degranulation: free extracellular granules with intact crystalloid cores, released by cell lysis rather than classical exocytosis.

Caruso, Caruso, Rigoli et al 2025, Cancers · CC BY 4.0 · source

Illustrations

Neutrophil, eosinophil, and basophil side by side, with nuclear shape and granule types labeled.

Neutrophil, eosinophil, and basophil side by side, with nuclear shape and granule types labeled.

Granulo / granulo.site · CC0

Neutrophil granule populations: azurophilic, specific, gelatinase, and secretory vesicles, with their contents and the order they are released.

Neutrophil granule populations: azurophilic, specific, gelatinase, and secretory vesicles, with their contents and the order they are released.

Granulo / granulo.site · CC0

NET formation: activation, oxidant burst, elastase and MPO entering the nucleus, PAD4 histone citrullination, chromatin release, and bacteria trapped.

NET formation: activation, oxidant burst, elastase and MPO entering the nucleus, PAD4 histone citrullination, chromatin release, and bacteria trapped.

Granulo / granulo.site · CC0

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